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Empowering scientists to pursue their riskiest, most exciting ideas.

The Chan Zuckerberg Biohub Network brings together researchers from across disciplines to pursue audacious, important scientific challenges.

Empowering scientists to pursue their riskiest, most exciting ideas. Empowering scientists to pursue their riskiest, most exciting ideas.

The CZ Biohub Network pursues grand scientific challenges on a 10- to 15-year time horizon to bring us closer to understanding the mysteries of the cell and how cells interact within systems.

San Francisco
Zebrahub: An Atlas of Vertebrate Development

CZ Biohub San Francisco researchers have built a powerful, interactive resource for understanding the developmental biology of the zebrafish, a small, transparent, genetically tractable, and validated model for human disease.

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San Francisco
Rapid Response: Partnering with Scientists Worldwide on Pathogen Surveillance

The Rapid Response team of CZ Biohub San Francisco empowers public health experts in the U.S. and low- and middle-income countries to use metagenomic sequencing and molecular epidemiology to detect, identify, and track emerging pathogens.

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Two scientists in lab looking at test tubes.

Join the CZ Biohub team!

Explore our open positions.

WATCH – Introducing the Chan Zuckerberg Biohub Chicago

cytoself

CZ Biohub scientists introduce cytoself, a deep-learning method that reveals information on protein localization and interactions

tabula sapiens

‘Tabula Sapiens’ Multi-Organ Cell Atlas Already Yielding Surprises for Biologists

New CZ Biohub-built ‘DaXi’ microscope – An advance in light-sheet imaging

New CZ Biohub-built ‘DaXi’ microscope – An advance in light-sheet imaging

WATCH – From parts list to blueprint: OpenCell lights the way

WATCH — The Fishpicker

The inaugural Chan Zuckerberg Biohub in San Francisco is focused on elucidating dynamic cell systems across scales, in health and disease.

TECHNOLOGY PLATFORMS
Bioengineering: A Culture of Hands-on Hacking and Building

Don’t have it? Build it. Our Bioengineering team built a UV microscope that could be a faster, cheaper, better way to diagnose malaria.

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INVESTIGATOR PROGRAM
Supporting Early-Stage, Risky Research

We provide unrestricted funding to world-renowned scientists, engineers, and technologists from Stanford University, UC Berkeley, and UCSF, giving these Investigators the freedom to pursue their visionary ideas.

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Chicago
Meet the Chicago Leadership

CZ Biohub Chicago is led by Professor Shana O. Kelley of Northwestern University.

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Shana O' Kelley, PhD, President of CZ Biohub Chicago
Chicago
zebrafish heart coronary vessel
Understanding Inflammation

CZ Biohub Chicago focuses on engineering technologies to make precise, molecular-level measurements of biological processes within human tissues, with an ultimate goal of understanding and treating the inflammatory states that underlie many diseases.

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CZ Biohub Chicago will use embedded sensors and probes to collect biological signals from human tissues with unprecedented resolution. This Biohub will study inflammation, a major driver of disease, and use this new measurement platform to learn how immune cells can malfunction and cause disease.

Chicago
zebrafish heart coronary vessel
Understanding Inflammation

CZ Biohub Chicago focuses on engineering technologies to make precise, molecular-level measurements of biological processes within human tissues, with an ultimate goal of understanding and treating the inflammatory states that underlie many diseases.

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CZ Biohub New York will harness and bioengineer immune cells for the early detection, prevention, and ultimately treatment of a wide variety of human diseases.

New York
Harnessing the Immune System

CZ Biohub New York will first harness the natural capabilities of our immune cells to detect and fix abnormalities in our bodies at very early stages. It will then bioengineer immune cells to create new capabilities to detect and potentially treat diseases, including cancers such as ovarian and pancreatic cancer and neurodegenerative diseases like Parkinson's or Alzheimer's, before they become untreatable.

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Human iPSC-derived macrophages. Markers are: DAPI (blue), actin (green), CD68 (magenta). Human iPSC-derived macrophages. Markers are: DAPI (blue), actin (green), CD68 (magenta).
New York
Meet the New York Leadership

CZ Biohub New York is led by Professor Andrea Califano of Columbia University.

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Catalysts of Change Icon Badge
Unraveling the mystery of brain infections

A Malaysian laboratory uses metagenomics to accelerate the diagnosis of neuroinfections...

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Speakers at This Generation Symposium 2022
Biohub Investigators
Diversity in academic hiring, a success story

NextGen initiative succeeds in diversifying faculty hiring in biological and biomedical sciences at ...

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Catalysts of Change Icon Badge
Bolivian biologists building a better future

Three generations of researchers visit Biohub SF...

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Biohub Investigators
Seeing the big picture

Intercampus team creates highly detailed images of one the world’s most prevalent parasites...

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Denise Lopez
Infectious Disease
Arming Public Health Practitioners with a Disease-Tracking Toolkit

Genomic epidemiology training empowered local health officials to respond to COVID and more...

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Our People
Learning to ‘speak amino acid’

The technology behind AI chatbots can unlock codes in human biology....

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News & Press

News
New partnerships to provide travel grants, coursework in genomic approaches to infectious disease for underrepresented aspiring physicians

CZ Biohub San Francisco partners with The 15 White ...

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Press
Can researchers use AI to take microscopy to the next level?

From virtual staining to lensless microscopes, researchers are capitalizing on artificial intelligence to rethink ...

Read More at Chemical & Engineering News
Press
Scientists launch amazing 'atlas' of embryos, showing how cells move and develop through time

"Zebrahub" is an atlas of cells in developing zebrafish embryos, and scientists say it will help us learn about our own biology, ...

Read More at Live Science
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