Cell Biology @ Scale 2024

When

Thursday, March 28, 2024 | 9:00 a.m. – 6:30 p.m. PT

where

UCSF Byers Auditorium, San Francisco, CA

This workshop is presented by the Chan Zuckerberg Biohub San Francisco in partnership with the Chan Zuckerberg Initiative.

Recent technological advances have transformed the scale at which cell biology can be conducted, from new imaging and “omics” strategies to the systematic engineering of genes and their expression. As a result, high-throughput, multiplexed approaches are greatly expanding the biological space that can be experimentally accessed. But the ability to conduct “cell biology at scale” is not simply an expansion of the number of experiments that can be performed – it represents a fundamental change in the way that such experiments can be conceived and the questions that can be answered.

To realize this potential, we need to re-evaluate core experimental goals, newly accessible biological questions, technological approaches, data collection, curation, dissemination, and effective strategies for computational analysis. We also need a collaborative, integrative, and interdisciplinary strategy to combine the capabilities and efforts from diverse laboratories for the robust sharing of techniques and datasets.

We are organizing the CB@S workshop to bring together a range of stakeholders from diverse disciplines to present recent developments and spark a robust discussion that will articulate key, actionable goals toward true cell biology at scale. For this workshop, we will also focus particularly on achieving large-scale cell biology across experimental scales – from the angstrom-level protein interactions that underlie cellular behaviors, to individual cells and differences across cell types, the interactions between cells within an organism, and emergent and collective cellular behaviors that are integrated at an organismal level.

Please register to attend in-person or virtually. A series of small talks will be selected from abstracts for in-person attendees.

Paul Blainey

Broad Institute & MIT

Iain Cheeseman

Whitehead Institute & MIT

Jonah Cool

Chan Zuckerberg Initiative

Manuel Leonetti

CZ Biohub SF

ALL TIMES IN PACIFIC TIME

Thu Thursday

March 28

Welcome remarks

9:00 - 9:10 a.m.

Steve Quake

Head of Science, Chan Zuckerberg Initiative

Session 1: Intracellular Systems

9:10 - 10:30 a.m.

Iain Cheeseman

Whitehead Institute & MIT

Emma Lundberg

Stanford University

Jan Ellenberg

EMBL

Lucas Pelkmans

University of Zürich

Break

10:30 - 11:00 a.m.

Coffee break

Session 2: Cellular Dynamics – from Molecules to Organisms

11:00 - 12:05 p.m.

Nike Walther

UC Berkeley

Samantha Morris

Washington University St. Louis

Sarah Bowling

Stanford University

Loïc Royer

CZ Biohub SF

Break

12:10 - 1:00 p.m.

Lunch

Session 3: Models & Networks

1:00 - 2:15 p.m

Trey Ideker

UC San Diego

Christina Theodoris

Gladstone Institutes

Markus Covert

Stanford University

Hana El-Samad

Altos Labs & UCSF

Break

2:15 - 2:30 p.m.

Coffee break

Session 4: Proteins: interactions, remodeling & predictions

2:30- 4:00 p.m.

Mikko Taipale

University of Toronto

Jared Rutter

The University of Utah & HHMI

Danielle Swaney

UCSF

Duo Peng

CZ Biohub SF

Erika Alden DeBenedictis

The Francis Crick Institute

Break

4:00 - 4:20 p.m.

Coffee break

Session 5: Engineering & Physics for Cell Biology at Scale

4:20 - 5:15 p.m.

Paul Blainey

Broad Institute & MIT

Taka Kudo

Genentech

Julie Theriot

University of Washington & HHMI

Reception

5:15 - 6:30 p.m.

Contact: cbas2024@czbiohub.org