Chan
Zuckerberg
Biohub
San Francisco
We bring together skilled and creative scientists and engineers to develop new technologies and tackle ambitious research projects, with the aim of understanding dynamic cell systems across scales in both healthy and diseased states. We also join forces with the Bay Area’s leading academic institutions to support bold, visionary science that can’t be done elsewhere.
Cells & Cell Systems
Cells are the fundamental unit of life. Our goal is to understand dynamic cell systems across scales, in both healthy and diseased states.
Dynamic …
We invent and apply state-of-the-art imaging technologies in living cells and organisms, and develop the computational tools to mechanistically interpret intracellular and intercellular behaviors.
across scales …
Our Research Groups explore cell systems at various scales, from molecules (metabolites, proteins, transcripts), to cells, tissues, organs, and whole organisms, to define cell types, states, and disease phenotypes.
At the grandest scale — in human populations — we enable pathogen surveillance and rapid outbreak response. In collaboration with experts at our partner institutions, both domestically and in low- and middle-income countries, we work to understand infectious disease and advance public health.
in health and disease
We map dynamic changes in cell behavior in response to disease and infection to define underlying mechanisms and to identify potential targets for therapeutic intervention and diagnostic tools.
And our Technology Platforms disseminate the technologies we develop — and the knowledge gained — world-wide through open-access publication and data portals.
INVESTIGATOR PROGRAM
Building community to catalyze innovation
The Investigator Program at CZ Biohub SF is funding research by world-renowned scientists, engineers, and technologists from Stanford University, UC Berkeley, and UCSF.
Learn More
Piecing together new technologies for biomedicine
As a young child in China, Zongjie (Daniel) Wang was a natural tinkerer. He built his own radio, and soon after, his own PC — both when he was only 10 years ...
A special visit with a nonagenarian expert in pathogenic amoebae
The UCSF lab of Joe DeRisi, CZ Biohub San Francisco president, has an active research program on the basic biology and clinical aspects of Balamuthia ...
Riddle of the sphinx
Why is the heart slightly on the left side of the body for most people? Why is DNA almost always a right-handed helix? Same with alpha helices, the building ...
Mind-blowing science: ‘Star Wars-style’ holograms to communicate with the brain
About 20 years ago, neuroscientists, recording from electrodes implanted in the medial temporal lobe, identified human brain cells that respond only to photos ...
Obsessed with the nucleus
Hawa Racine Thiam was 22 years old when her obsession with cell nuclei began. It was early in her master’s studies, at a poster session hosted by her ...
Unraveling the mystery of brain infections
In April 1997, a one-year-old child was admitted to Sibu Hospital in Sarawak, Malaysia with fever and mouth ulcers, symptoms suggestive of an illness known as ...
Diversity in academic hiring, a success story
In the summer of 2020, after the murder of George Floyd by a police officer in Minneapolis, many institutions around the country were reflecting on how ...
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A CHAN ZUCKERBERG SCIENCE INSTITUTE
